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16 · Chapter

Cancer

One in two people in the UK will develop cancer in their lifetime. Around four in ten cases are preventable — and survival has doubled in the last 50 years.

Key facts and figures
The big four

Breast, prostate, lung and bowel

Breast, prostate, lung and bowel cancers together account for over half of all new cases in the UK. Lung cancer remains the leading cause of cancer death.[1]CRUK

Prevention

Four in ten cases are preventable

A landmark BJC analysis attributed 38% of UK cancers to modifiable factors: smoking (15%), overweight/obesity (6%), UV radiation (4%), alcohol (3%), occupational exposures, infections (HPV, H. pylori), low fruit & vegetable intake, processed meat and physical inactivity.[5]Brown et al., BJC 2018

Early diagnosis

NICE NG12 and the 'red flags'

NICE NG12 sets the symptom thresholds for urgent suspected-cancer referrals (the 2-week-wait pathway) — for example, unexplained rectal bleeding in adults aged 50+, postmenopausal bleeding, or a breast lump in women aged 30+.[4]NICE NG12

Screening

Three national programmes

The UK offers national screening for bowel, breast and cervical cancer, with a targeted lung cancer screening programme rolling out for ever-smokers aged 55–74. See our Preventive Care chapter for full eligibility.[1]CRUK

References
  1. [1] Cancer Research UK. Cancer statistics for the UK · 2024
  2. [2] NHS. Cancer — overview · 2024
  3. [3] Office for National Statistics. Cancer registration statistics, England · 2024
  4. [4] NICE. Suspected cancer: recognition and referral — NG12 · 2023
  5. [5] Brown et al., British Journal of Cancer. The fraction of cancer attributable to modifiable risk factors in the UK · 2018