
Coronary Artery Disease
Coronary artery disease, also called coronary heart disease, happens when the arteries supplying the heart muscle become narrowed by fatty deposits. It can cause angina and heart attacks. This page explains the warning signs, when to call 999, how it is diagnosed and treated, and what helps day to day.
What this page covers
This is general information for people in the UK. It is not a diagnosis and it does not replace advice from your GP, pharmacist, cardiology team or NHS 111. If you think someone may be having a heart attack, stop reading and call 999 now.[1]NHS — coronary heart disease
Possible heart attack — call 999 now
Call 999 immediately and ask for an ambulance if you or someone else has:
- chest pain that feels like pressure, heaviness, tightness or squeezing
- pain that spreads to one or both arms, the jaw, neck, back or stomach
- shortness of breath
- sweating, often with clammy or grey-looking skin
- feeling sick or being sick
- feeling light-headed, dizzy, or collapsing
- a strong sense that something is seriously wrong
Symptoms vary between people. A heart attack can happen without severe chest pain — for some people the main symptoms are breathlessness, sickness, sweating, indigestion-like discomfort or extreme tiredness. If you are unsure, still call 999. It is always better to be checked.[2]NHS — heart attack
Do not drive yourself to hospital and do not wait to see if the symptoms pass. While you wait for the ambulance, sit down and rest. The 999 call handler will tell you what to do, which may include taking aspirin if it is safe for you — follow their instructions rather than acting on your own. If someone becomes unresponsive and is not breathing normally, start CPR and ask for a defibrillator.[10]NHS — CPR
Key points
- Coronary artery disease is caused by narrowing of the heart’s own arteries.
- Angina is chest discomfort caused by that narrowing; a heart attack is a sudden blockage.
- Angina that is new, worse, more frequent or happening at rest needs urgent assessment.
- Symptoms can be less typical in women, older people and people with diabetes.
- Treatment usually combines lifestyle support, medicines and sometimes a procedure.
- Never stop prescribed heart medicine without professional advice.
What coronary artery disease is
The coronary arteries carry blood to the heart muscle itself. Over years, fatty material can build up in the artery wall. This process is called atherosclerosis, and the deposits are often called plaques. As arteries narrow, the heart muscle may not get enough oxygen-rich blood when it is working harder.[1]NHS
- Angina — chest pain, tightness or discomfort caused by reduced blood flow, usually brought on by exertion, cold weather, a heavy meal or emotional stress, and usually easing with rest or with prescribed spray or tablets.[3]NHS — angina
- Heart attack (myocardial infarction) — a plaque ruptures and a clot forms, suddenly blocking blood flow. Heart muscle starts to be damaged, so treatment is time-critical.[2]NHS — heart attack
- Acute coronary syndrome — the term used in hospital for the range of sudden events including unstable angina and heart attack, each with its own treatment pathway.[14]NICE NG185
- Heart failure and rhythm problems — damaged or poorly supplied heart muscle can later lead to heart failure or an irregular heartbeat, which have their own treatments.[1]NHS
Stable angina versus unstable symptoms
Stable angina follows a pattern you recognise: it comes on with a predictable amount of effort or stress, feels similar each time, and settles within a few minutes of resting or using your prescribed medicine.[3]NHS — angina
Unstable symptoms are different: chest discomfort that is new, more severe, lasts longer, comes on with less effort than before, happens at rest or wakes you at night, or does not settle in the usual way. This is a warning sign and must be assessed urgently.[14]NICE NG185
Which number to call
- 999 now — chest pain or pressure that is severe, lasts more than about 15 minutes, or comes with breathlessness, sweating, sickness, collapse or pain spreading to the arms, jaw, neck, back or stomach. Also 999 if angina does not settle after resting and using your prescribed medicine as your team has instructed.
- NHS 111, or an urgent GP appointment the same day — angina that is happening more often, coming on with less effort, or feels different from usual, but has settled and you have no emergency symptoms. NHS 111 is free and open 24 hours a day.[11]NHS 111
- Routine GP appointment — chest discomfort, breathlessness or unusual tiredness on exertion that has been building up over weeks, so it can be investigated properly. Do not put this off.[13]NICE — chest pain of recent onset
Do not drive yourself anywhere if you have emergency symptoms.
Symptoms that are easy to miss
Heart attacks and angina do not always look like the dramatic version people picture. Anyone can have less typical symptoms, but they are reported more often in some groups, so it is worth knowing about them.[2]NHS — heart attack
- Women — chest pressure is still the commonest symptom, but breathlessness, sickness, sweating, jaw or back discomfort and unusual fatigue may be more prominent, and symptoms are sometimes put down to indigestion, anxiety or stress. If something feels wrong, ask to be checked and say clearly that you are worried about your heart.
- Older people — symptoms can be vaguer: breathlessness, sudden confusion, weakness, fainting or simply feeling very unwell, sometimes without much pain at all.
- People with diabetes — nerve changes can blunt pain, so a heart attack may cause little or no chest pain. Unexplained breathlessness, sweating, sickness or sudden loss of energy should be taken seriously.
None of this means a symptom always appears in a particular group. It means that if something feels seriously wrong, you should not talk yourself out of calling for help.
What increases the risk
Risk builds up over time and usually involves several factors together. Some can be changed and some cannot, and having risk factors does not mean you will definitely develop heart disease.[12]NICE NG238
- smoking, and exposure to other people’s smoke
- high blood pressure
- raised cholesterol and other blood fats
- diabetes and prediabetes
- chronic kidney disease
- a family history of early heart disease, and inherited conditions such as familial hypercholesterolaemia
- getting older
- living with obesity, and carrying weight around the middle
- being inactive for most of the day
- an eating pattern high in saturated fat, salt and ultra-processed food
- drinking above the UK low-risk guidelines
- long-term stress, poor sleep and some inflammatory conditions
- ethnic background, and social and financial pressures that make healthy choices harder
Adults in England aged 40 to 74 without certain existing conditions are usually invited for an NHS Health Check, which includes a cardiovascular risk assessment. Similar checks are available in other UK nations — ask your GP surgery.[8]NHS Health Check
How it is investigated
No single test tells the whole story. A clinician puts together your history, an examination and tests chosen for your situation.[13]NICE — chest pain of recent onset
History and examination
You will be asked what the discomfort feels like, what brings it on, how long it lasts, what relieves it, and about risk factors and family history. Blood pressure, pulse, weight and heart sounds are usually checked. Being specific about your symptoms genuinely helps — it is worth writing them down before the appointment.
ECG (electrocardiogram)
A quick, painless recording of the heart’s electrical activity. It can show signs of a heart attack, previous damage or rhythm problems. A normal ECG does not always rule out coronary artery disease, so other tests may still be needed.[14]NICE NG185
Blood tests
In suspected heart attack, hospitals measure troponin, a protein released when heart muscle is damaged, usually more than once. Other blood tests may check cholesterol, blood glucose or HbA1c, kidney function, thyroid function and anaemia.[14]NICE NG185
CT coronary angiography
A CT scan with contrast dye that shows the coronary arteries. NICE recommends it as a first-line test for many people with stable chest pain that may be angina. You may be given medicine to slow the heart rate for the scan.[13]NICE — chest pain of recent onset
Other tests where appropriate
- Echocardiogram — an ultrasound of the heart’s structure and pumping.
- Stress imaging — imaging during exercise or medicine-induced stress, to see how blood flow changes.
- Invasive coronary angiogram — a catheter and dye study that shows narrowings directly, and can sometimes be combined with treatment in the same visit.
- Heart-rhythm monitoring — a portable monitor worn for a period of time.
Waiting times and local pathways vary, so ask your team what happens next and who to contact if symptoms change while you wait.
How coronary artery disease is treated
Treatment aims to relieve symptoms, reduce the chance of a heart attack, and protect the heart muscle. For most people it combines lifestyle support and medicines, with a procedure for some.[1]NHS
Lifestyle support
- Stopping smoking is one of the single most effective steps, and free NHS support makes it far more likely to work.
- Regular activity within the limits your team advises, built up gradually.
- An eating pattern lower in saturated fat and salt, with more vegetables, fruit, pulses and wholegrains.
- Keeping within the UK low-risk alcohol guidelines, and getting help if cutting down is hard.
- Treating high blood pressure, cholesterol and diabetes as your team advises.
- Sleep, stress and mood matter too, and are a legitimate thing to raise with your GP.
Medicines used in coronary artery disease
Which medicines are right depends on your diagnosis, other conditions and what you already take. Common groups include:
- Antiplatelets such as aspirin or clopidogrel, to make clots less likely.
- Statins and other lipid-lowering treatments, to reduce cholesterol and cardiovascular risk.[7]NHS — statins
- Beta blockers, which reduce how hard the heart works.
- Nitrates, including a spray or tablet used for angina attacks and before activity that usually brings symptoms on.
- ACE inhibitors or similar medicines, often used after a heart attack or with high blood pressure.
- Calcium channel blockers and other anti-anginal medicines, where suitable.
We do not publish doses or personalised instructions. Your prescriber decides these, and the leaflet in your medicine pack explains how to take it. A pharmacist can review everything you take, including anything bought over the counter, and offer a free medicines check.[12]NICE NG238
Angioplasty and stents
Coronary angioplasty (PCI) opens a narrowed artery using a small balloon, usually leaving a stent in place to hold it open. It is often used as an emergency treatment for a heart attack, and sometimes planned for angina that is not controlled by medicines.[5]NHS — coronary angioplasty
Afterwards, people are normally prescribed antiplatelet medicines for a period decided by the cardiology team. Taking them exactly as prescribed matters — stopping early can be dangerous. Ask your team before any dental work or surgery.
Coronary artery bypass graft (CABG)
Bypass surgery uses a blood vessel from elsewhere in the body to route blood around a blocked section of artery. It may be recommended when several arteries are affected or when the pattern of disease suits surgery better than stenting. Recovery takes longer than angioplasty and includes a structured rehabilitation plan.[6]NHS — CABG
Medicine safety — never stop heart medicine on your own
Do not stop, skip, reduce or change any prescribed heart medicine because of side effects, cost, something you have read, or because you feel better. Stopping suddenly — particularly antiplatelets after a stent, or beta blockers — can be dangerous.
If a medicine is causing problems, speak to your GP, pharmacist or cardiology team. There are usually alternatives, and they can review the whole list with you. If you run out or cannot afford your prescriptions, ask the pharmacy about emergency supply and prescription prepayment options rather than going without.[7]NHS — statins
Recovery after a heart attack or procedure
Recovery is a process, not a single moment. Most people are offered a structured cardiac rehabilitation programme, and it is worth taking up even if you feel well.[4]NHS — recovery after a heart attack
Cardiac rehabilitation
Programmes usually combine supervised exercise, education about your condition and medicines, and emotional support, delivered in a group, at home or online. They are designed for people who have had a heart attack, stent, bypass surgery or a diagnosis of angina. Ask your team how to be referred if you have not been offered a place.[4]NHS
Going back to work
When you can return depends on your treatment, your recovery and the kind of work you do. A phased return, adjusted duties or shorter hours are common. Your GP can issue a fit note with suggestions for your employer, and occupational health can help where it is available.
Driving and the DVLA
Rules differ depending on the event or procedure, your symptoms and the type of licence you hold, and they are stricter for bus, coach and lorry licences. Some situations require you to stop driving for a period, and some must be reported to the DVLA. Check the official GOV.UK guidance for your exact situation and follow the advice your cardiology team gives you.[15]GOV.UK — health conditions and driving (DVLA)
Sex and relationships
Most people can return to sexual activity as they recover, and many find that if they can manage moderate everyday exertion comfortably they can manage sex. Worry, tiredness and changes in confidence are common for both partners, and some heart medicines can affect erections or desire.
Please ask your cardiac rehabilitation team or GP rather than guessing — this is a routine question for them. Important: some erectile dysfunction medicines must never be taken with nitrates. Always check with a doctor or pharmacist first, and never buy such medicines online without advice.
Emotional wellbeing
Anxiety, low mood, poor sleep and fear of another event are extremely common after a cardiac event, and they affect partners and family too. This is not weakness, and it is treatable.
- Tell your GP or rehab team if worry or low mood is affecting daily life.
- NHS talking therapies can be accessed via your GP, and in England you can usually self-refer.
- The British Heart Foundation is a charity, not an NHS service, and offers information and support — please check current contact details on its website.[17]BHF
Reducing risk, before and after diagnosis
- Stop smoking, with free NHS support — the benefits begin quickly.
- Know your blood pressure, and have it checked as advised.
- Know your cholesterol result and what your team wants it to be for you.
- If you have diabetes or kidney disease, keep your reviews up to date.
- Build regular activity into the week, at a level your team says is safe.
- Take up your NHS Health Check invitation if you are offered one.
- Tell your GP about a family history of early heart disease — it can change what is offered to you.
- Take prescribed medicines consistently, and ask for a review if they are hard to manage.
Practical checklist
- Learn the heart-attack warning signs, and that they are not always severe chest pain.
- Call 999 rather than driving yourself or waiting to see if it passes.
- Keep your angina spray or tablets with you and know exactly how your team told you to use them.
- Keep an up-to-date medicines list and take it to every appointment and hospital visit.
- Ask to be referred to cardiac rehabilitation if it has not been offered.
- Check the DVLA rules that apply to your situation and licence.
- Ask about a free pharmacy medicines review if you take several medicines.
- Ask for an interpreter, easy-read information or large print if that would help.
- Contact your team early if symptoms change, rather than waiting for the next appointment.
Useful official services
In a life-threatening emergency, always call 999.
Other pages that may help
Please speak to a healthcare professional
Sixpence Support UK provides general information only. We cannot examine anyone, give a diagnosis, or recommend medicines or doses, and this page is not a substitute for advice from a qualified healthcare professional. Please do not start, stop or change prescribed treatment on the basis of information found online. If symptoms are severe, worsening or worrying you, contact your GP, pharmacist, cardiology team or NHS 111 — and call 999 in an emergency.
Trusted organisations and further support
Independent UK organisations for heart conditions
These are separate organisations, not NHS services. Please take telephone numbers and opening hours from their own current pages. Each button opens the organisation’s official website in a new tab.
These organisations are independent of Sixpence Support UK. Their inclusion is for information and signposting and does not imply a partnership or endorsement.
- [1] NHS. Coronary heart disease · 2026
- [2] NHS. Heart attack · 2026
- [3] NHS. Angina · 2026
- [4] NHS. Heart attack — recovery and cardiac rehabilitation · 2026
- [5] NHS. Coronary angioplasty and stent insertion · 2026
- [6] NHS. Coronary artery bypass graft (CABG) · 2026
- [7] NHS. Statins · 2026
- [8] NHS. NHS Health Check · 2026
- [9] NHS. Better Health — quit smoking · 2026
- [10] NHS. CPR — first aid · 2026
- [11] NHS 111. Get help for your symptoms (England) · 2026
- [12] NICE. Cardiovascular disease: risk assessment and reduction, including lipid modification (NG238) · 2023
- [13] NICE. Chest pain of recent onset: assessment and diagnosis (CG95) · 2016
- [14] NICE. Acute coronary syndromes (NG185) · 2020
- [15] GOV.UK / DVLA. Health conditions and driving (includes heart conditions) · 2026
- [16] GOV.UK / DVLA. Tell DVLA about a medical condition that affects your driving · 2026
- [17] British Heart Foundation. Information and support (charity, not an NHS service) · 2026
