
Depression
A calm, plain-English United Kingdom guide to depression — what it can feel like, when to speak to a GP, the treatments that may be offered, antidepressant safety, everyday practical support, and where to get urgent help across all four UK nations.
Reviewed August 2026
What depression is
Depression is more than having a difficult day or feeling sad for a short while. It is a real health condition that can affect mood, interest and pleasure, energy, sleep, appetite, concentration, confidence, relationships, work and ordinary everyday tasks such as washing, cooking or replying to messages.
Depression is not weakness, laziness or attention-seeking, and it is not something a person can simply “snap out of”. It is not a character flaw, and needing help with it is not a failing.
People experience depression differently. Some feel deeply sad; others feel flat, numb, irritable or exhausted. Symptoms can be mild, moderate or severe, and can change over time. Nobody has to have every symptom described on this page. This page gives general information only — it cannot tell anyone whether they have depression.
Immediate danger — call 999 or go to A&E now
Please call 999 or go to A&E straight away if:
- someone is in immediate danger of ending their life or being seriously harmed
- someone has seriously harmed themselves, taken an overdose, or swallowed something harmful — even if they seem alright now
- someone cannot keep themselves or another person safe right now
- there is severe confusion, hallucinations or beliefs that are putting someone in immediate danger
You will not be wasting anyone's time. Emergency services would far rather be called early. If you are unsure, please make the call.
Urgent mental health help today
This is for someone who feels mentally unsafe, severely distressed or unable to cope, but who is not in immediate life-threatening danger. Help is available today, at any hour.
- England: call NHS 111 and choose the mental health option, or use NHS 111 online.
- Scotland: call NHS 24 on 111.
- Wales: call NHS 111 and press option 2 for the mental health service.
- Northern Ireland: call Lifeline on 0808 808 8000.
Anywhere in the UK, at any time of day or night:
- Samaritans — 116 123 (free, 24 hours a day, every day)
- Shout — text SHOUT to 85258 (free, 24-hour text support)
- Childline — 0800 1111 for children and young people (free, 24 hours)
Key points
- Depression can affect thoughts, feelings, the body and daily life.
- People can look as though they are coping while struggling privately.
- Effective help is available, and most people improve with the right support.
- Treatment should be discussed and chosen with the person, not simply handed out.
- Recovery is not always a straight line — better weeks and harder weeks are normal.
- Suicidal thoughts need to be taken seriously and talked about openly.
- Depression can happen alongside anxiety, physical illness, disability, bereavement, money problems, loneliness or other difficulties.
Depression, sadness and grief
Sadness is a normal human feeling. It usually comes in waves, has a reason attached to it, and eases as circumstances or thoughts change. Depression tends to be more persistent, affects many areas of life at once, and often takes away interest, energy and hope rather than only causing sadness.
Grief does not follow a timetable and there is no correct way to mourn. Intense sadness, tearfulness, poor sleep and loss of appetite after a bereavement do not automatically mean someone has clinical depression. Grief often comes in waves and usually allows moments of comfort or connection.
However, grief and depression can happen together. If low mood is constant, if someone feels worthless or hopeless about the future, or if they have thoughts of suicide, that deserves medical help — whether or not it is “only grief”.
Signs and symptoms
Depression shows itself in different ways. Someone may notice several of the following, most of the day, on most days, for two weeks or longer.
Emotional signs
- persistent low mood, sadness or a feeling of emptiness
- losing interest or pleasure in things that normally matter
- hopelessness, guilt, feeling worthless or a burden
- irritability, tearfulness or feeling on edge
- feeling numb rather than visibly sad
Thinking
- poor concentration and trouble following conversations, television or reading
- difficulty making decisions, even small everyday ones
- memory feeling unreliable, or the mind feeling slow or foggy
- very self-critical thoughts
Physical signs
- low energy, tiredness, or feeling physically slowed down
- sleep changes — sleeping far less, waking very early, or sleeping much more
- appetite or weight changes in either direction
- reduced interest in sex
- unexplained aches, headaches, stomach problems or general physical discomfort
Behaviour and daily life
- withdrawing from people, avoiding calls, messages or visits
- struggling with washing, dressing, eating, housework, work or education
- letting post, bills or appointments build up
- using more alcohol or drugs to cope
- thoughts of death, self-harm or suicide
If there are thoughts of suicide or self-harm, please treat that as a reason to get help now rather than later. It is not dramatic or attention-seeking to ask for help.
Keep a record
A short written record often makes an appointment easier, especially when speaking feels hard. It is simply a way of remembering things — it is not a diagnostic test, questionnaire or risk score.
- what the symptoms are, and roughly when they started
- sleep — how long, how broken, waking times
- appetite, eating and any weight change
- any medication changes, including anything bought over the counter
- important events or pressures — loss, illness, money, work, relationships
- how daily activities are affected — washing, cooking, going out, working, caring for others
- anything that has helped, even slightly
When to speak to a GP
Please consider speaking to a GP when symptoms have persisted for around two weeks or more, when they keep coming back, when they are becoming hard to manage, or when they are interfering with everyday life.
Nobody needs to wait until they are in crisis, and nobody needs to prove that things are “bad enough”. Getting help earlier usually makes things easier.
These two sentences are enough to start the conversation:
- “I have been feeling low and it is affecting my everyday life. I need help.”
- “Talking is difficult for me. I have written down what has been happening.”
They can be read out, shown on a phone screen, handed over on paper, or sent through an online consultation form.
What a GP or clinician may ask
An assessment is a conversation, not a test. A clinician may ask about:
- the symptoms, how long they have lasted and how severe they feel
- how daily life, work, study, relationships and self-care are affected
- physical health, including tiredness, pain, thyroid problems or long-term conditions
- current medicines, including anything recently started or stopped
- alcohol, recreational drugs and caffeine
- past episodes of low mood, and anything that has helped before
- family history of depression, bipolar disorder or other mental illness
- recent stressful or traumatic events, loss, money or housing pressures
- safety — including any thoughts of self-harm or suicide
- who is around for support at home
Some physical conditions and medicines can cause or worsen symptoms that look like depression, so a clinician may suggest an examination or blood tests where that seems appropriate. There is no single blood test or scan that diagnoses depression — diagnosis is based on the full picture described in the conversation.
Different patterns of depression
Depression is described in different ways depending on how severe it is, how often it happens and what else is going on. These descriptions help clinicians choose treatment with the person.
Less severe and more severe depression
Current NHS and NICE guidance describes depression as less severe or more severe, based on the number and intensity of symptoms and how much daily life is affected — not on how “deserving” someone is of help.
For less severe depression, guided self-help, group support, structured exercise programmes or talking therapy are often suggested first. For more severe depression, a combination of talking therapy and medicine is more commonly offered, and specialist support may be involved.
A first episode and recurrent depression
Many people have a single episode and recover well. Others experience recurrent depression, where episodes return after periods of feeling well.
Telling a clinician about previous episodes matters: it can change the treatment offered, how long treatment continues and what is planned to reduce the chance of relapse.
Persistent or long-term depression
Some people live with a lower-level but long-lasting depression for years, sometimes assuming it is simply their personality. It can still be treated, and treatment may take a longer, steadier approach.
It is worth saying plainly to a clinician: “this has been going on for years, not weeks”. That information changes what is offered.
Seasonal pattern depression
Some people find depression follows a seasonal pattern, most often becoming worse in autumn and winter, with improvement in spring and summer. Symptoms may include heavy tiredness, sleeping more, craving carbohydrates and withdrawing.
It is treated seriously in the same way as other depression. Keeping a note of which months are hardest helps a clinician plan ahead rather than react late.
Depression during pregnancy and after birth
Depression can begin during pregnancy (antenatal) or after birth (postnatal), and it can affect birthing parents, partners and adoptive parents.
It is common, it is treatable, and it does not mean someone is a bad parent. A midwife, health visitor or GP can help, and specialist perinatal mental health services exist across the UK.
Depression with psychotic symptoms
Occasionally, severe depression comes with psychotic symptoms — hearing or seeing things others do not, or holding strong beliefs that are not based in reality, often about guilt, illness or punishment.
This needs urgent specialist assessment. If someone is in immediate danger because of these experiences, call 999 or go to A&E.
Depression alongside a long-term physical condition
Depression is more common in people living with long-term conditions such as heart disease, diabetes, kidney disease, arthritis, chronic pain, cancer or neurological conditions.
Physical symptoms should not be dismissed as “just depression”, and low mood should not be dismissed as “understandable given everything”. Both deserve proper attention.
Depression in bipolar disorder
Some people who experience depression also have periods of unusually high or irritable mood, a reduced need for sleep, racing thoughts, talking much faster than usual, excessive energy, unusual confidence, overspending or other impulsive behaviour.
These periods must be mentioned to a clinician, even if they felt good at the time or happened years ago. Please do not try to diagnose yourself or anyone else — this is information for a professional to consider.
It matters because treatment for bipolar depression can be different from treatment for depression alone, and some treatments are chosen or avoided on that basis.
Causes and contributing factors
Depression usually results from several things acting together rather than one single cause. Nobody brings depression on themselves.
- Biological: family history, physical illness, chronic pain, disability, hormonal changes, thyroid problems, some medicines, long-term poor sleep.
- Psychological: trauma, abuse, neglect, long-term stress, very self-critical thinking, previous episodes of depression or anxiety.
- Social: bereavement, loneliness and isolation, discrimination and racism, caring responsibilities, work pressure or job loss, poor or unstable housing, money worries and debt, relationship breakdown.
- Alcohol and drugs: both can deepen low mood over time, even when they help briefly.
Sometimes there is no single clear cause at all. Depression can arrive when life appears to be going well, and that does not make it less real or less treatable.
Treatment choices
Treatment depends on how severe the depression is, what the person prefers, what has been tried before, other health conditions, and any risk to safety. There should be a conversation and a choice, not a single option handed over.
We do not give medicine names or doses, and we cannot say which treatment is right for any individual. No single treatment suits everyone.
Guided self-help
Structured self-help materials — workbooks, online programmes or apps — used alongside brief support from a trained practitioner. Often offered for less severe depression, and usually available without a long wait.
Talking therapies
Talking therapies are a mainstay of depression treatment. In England, people can self-refer to NHS Talking Therapies without seeing a GP first. Scotland, Wales and Northern Ireland have their own referral routes, usually through a GP or a local service.
Behavioural activation
A practical therapy that works on the link between activity and mood. It gently rebuilds routine and meaningful activity in very small, planned steps, rather than waiting to feel motivated first. It is often recommended and can be very effective.
Cognitive behavioural therapy (CBT)
CBT looks at how thoughts, feelings and behaviour affect each other, and helps someone test and change unhelpful patterns. It may be delivered one to one, in a group, or online with practitioner support.
Interpersonal therapy and counselling
Interpersonal therapy focuses on relationships, roles, conflict and loss. Counselling for depression gives space to explore feelings and difficult experiences. Either may be appropriate depending on what is driving the depression and what the person prefers.
Antidepressants
Antidepressants may be offered, particularly for more severe depression, for depression that has not improved with other treatment, or where someone has found them helpful in the past. They are prescribed and reviewed by a clinician, who should explain the likely benefits, possible side effects and how long treatment may continue.
Please read the medicine-safety panel below before making any change to a prescription.
Combining medicine and psychological treatment
For more severe or persistent depression, a combination of medicine and talking therapy is often more effective than either alone. Choosing both is not a sign that things are hopeless — it is a common and reasonable plan.
Specialist mental health support
A GP may refer to a community mental health team or another specialist service where depression is severe, complex, long-lasting, involves psychosis or bipolar disorder, or where there are safety concerns. Specialist perinatal, older people's and young people's services also exist.
Treatment when previous options have not helped
If depression has not responded to earlier treatment, a clinician may review the diagnosis, consider a different therapy, change or add medicine, or refer for specialist assessment. Other treatments exist for severe or treatment-resistant depression and are decided by specialists with the person.
Not improving yet does not mean nothing will work.
Preventing relapse and making a staying-well plan
A staying-well plan is written while things are steadier, and usually includes:
- early warning signs that are personal to that person
- what has helped before, and what has not
- who to contact, and how quickly
- sleep, routine, alcohol and workload
- when to ask for a medication or therapy review
Antidepressant safety — please read carefully
- Antidepressants help some people a great deal, but benefits and side effects vary from person to person.
- Improvement usually takes time — often a few weeks before a clear difference is felt, and side effects sometimes appear before the benefit does.
- Some people feel more agitated, anxious, restless or notice new or worsening thoughts of self-harm or suicide, particularly in the early weeks or after a dose change. Seek urgent medical advice if this happens.
- Please do not stop, reduce, double or change an antidepressant without speaking to the prescriber first.
- Stopping suddenly can cause withdrawal symptoms such as dizziness, flu-like feelings, sleep problems, electric-shock sensations, anxiety or irritability.
- When stopping is right, it is normally done as a gradual, individually planned reduction, at a pace that suits the person, with review along the way.
- Antidepressants are not addictive in the way alcohol or street drugs are — they do not cause cravings or a compulsion to take more. However, the body can become used to them, which is why withdrawal symptoms can occur when they are stopped too quickly. Dependence in this sense is not the same as addiction.
- After an overdose or a serious reaction, call 999 or go to A&E immediately.
If treatment is not helping
- Say so honestly to the GP, prescriber or therapist. Being polite about it can hide how bad things are.
- Ask when improvement might reasonably be expected, and what should happen if it does not come.
- Discuss side effects openly and whether the treatment is realistically manageable.
- Ask about another approach, combination treatment, or specialist assessment.
- Do not stop medication suddenly — ask for a planned review instead.
- Seek urgent help straight away if safety is getting worse.
Everyday support
None of the following cures depression, and none of it replaces treatment. They are simply things that can make difficult days a little more manageable.
- Break tasks into very small steps — “put one plate in the sink”, not “clean the kitchen”.
- Keep food, drinks and prescribed medication within reach.
- Aim for a basic daily routine: rough wake time, one meal, one small task.
- Get some daylight and gentle movement where that is possible.
- Reduce alcohol and recreational drugs, which usually deepen low mood.
- Keep contact with one trusted person, even briefly by text.
- Prepare simple food — tinned, frozen or ready-made is entirely fine.
- Where possible, avoid major decisions during the worst periods.
- Use reminders, written notes or phone alarms for medication and appointments.
Advice such as “just think positively”, “cheer up” or “go for a walk and you will feel better” is not helpful and is not what this page is saying.
Helping someone with depression
- Listen without judgement. Being heard helps more than advice. Avoid rushing to fix things.
- Ask directly about suicide if you are worried: “Are you thinking about suicide?” Asking does not put the idea into someone's head — it usually brings relief and opens a conversation.
- Offer practical help: a lift, shopping, a meal, sitting with post, looking after children for an hour.
- Help them contact services — booking the appointment, sitting in on the call, or going along.
- Call emergency help when there is immediate danger. Call 999.
Supporters and carers also need rest and support. It is not selfish to take breaks, keep your own routine, or talk to someone yourself.
If someone refuses help
Adults have the right to make their own decisions, including refusing treatment. Pressuring someone often closes the conversation down. Staying in contact, asking again gently another day, and offering to help with the practical parts often achieves more.
That is different from an emergency. If there is immediate danger to life, call 999 or go to A&E — that is the right thing to do even if the person says not to. If safety is uncertain, get urgent professional advice the same day rather than carrying the worry alone.
Depression in children and young people
Depression in young people can look different from depression in adults. It may show as:
- irritability, anger or being easily upset rather than obvious sadness
- withdrawing from friends, family or activities they used to enjoy
- falling school or college attendance, or a drop in schoolwork
- sleep changes, tiredness or difficulty getting up
- unexplained headaches, stomach aches or other physical complaints
- hopelessness about the future, or self-harm
If you are a young person reading this: you can speak to a parent or carer, a trusted adult, a teacher, your school's safeguarding lead, a GP, or Childline on 0800 1111. You can also text SHOUT to 85258. If you are in immediate danger, call 999.
This is nobody's fault — not the young person's, not their parents', not their school's. It is a health problem that responds to help.
Depression during pregnancy and after birth
Antenatal depression (during pregnancy) and postnatal depression (after birth) are common and treatable. They are not a sign of failing as a parent, and they are not caused by lack of love for the baby.
Symptoms can include persistent low mood, tearfulness, exhaustion beyond normal tiredness, anxiety, trouble bonding, guilt, or frightening thoughts. Partners can also become depressed.
Please tell a midwife, health visitor or GP. Specialist perinatal mental health support exists across the UK, and asking for help does not put anyone at risk of losing their baby.
Urgent — possible postpartum psychosis
Rarely, a new parent develops postpartum psychosis. This is a medical emergency and needs urgent, same-day specialist help. Warning signs include:
- severe confusion or not making sense
- hallucinations — hearing or seeing things others do not
- delusions — strong beliefs that are not based in reality
- extreme mood changes, elation, agitation or not sleeping at all
- behaviour that puts the parent or baby in danger
Contact the GP, midwife, health visitor or local perinatal mental health team the same day. If there is immediate danger, call 999 or go to A&E.
Depression in older people
Depression is not an inevitable part of ageing and should never be dismissed as “just getting old”. In later life it may show as:
- loss of interest in people, hobbies or going out
- poor sleep or waking very early
- low energy and slowed movement
- memory or concentration problems, which can be mistaken for dementia
- physical complaints such as pain, stomach problems or dizziness
- withdrawing, or neglecting food, warmth, hygiene or medication
Bereavement, loneliness, caring for a partner, retirement, illness, reduced mobility and hearing or sight loss can all contribute. A medication review is worth asking about, since some medicines can affect mood. None of this means older people are fragile or beyond help — treatment works well in later life.
Disabled and neurodivergent people
Disabled and neurodivergent people often face extra barriers to getting help with depression. These are service problems, not personal failings.
- Communication barriers — phone-only booking, rushed appointments, or no accessible format.
- Diagnostic overshadowing — symptoms being wrongly explained away by an existing diagnosis, disability or autism, rather than being assessed.
- Inaccessible services — steps, distance, transport, or therapy delivered in a way that does not work for the person.
- Sensory needs and fatigue — bright lights, noise, long waits and back-to-back appointments.
It is reasonable to ask for adjustments, for example: written or email communication instead of phone calls; extra appointment time; a quiet waiting area or first/last appointment of the day; easy-read or large-print information; and bringing a supporter or advocate where the service permits.
Long-term illness and pain
Depression and physical health affect each other in both directions. Living with pain, fatigue, disability or a serious diagnosis makes depression more likely; depression in turn can worsen pain, sleep, appetite, activity and recovery.
New or changing physical symptoms should be properly assessed and never automatically dismissed as “just depression”. Equally, low mood alongside a physical illness deserves treatment in its own right.
Work, education, money and housing
Depression rarely stays inside the consulting room. Work, study, money and housing are often part of both the cause and the recovery.
- Work: an employer, occupational health service or HR team may be able to agree adjustments such as changed hours, reduced duties, a phased return or more flexible working. A fit note from a GP can state that someone may be fit for work with adjustments, not only that they are unfit.
- Education: schools, colleges and universities have student support, wellbeing or disability teams, and can often adjust deadlines, attendance expectations or exam arrangements.
- Access to Work: a government scheme that may provide support or funding for people whose mental health affects their work. Eligibility depends on individual circumstances.
- Money: benefits and other financial help may be available, and specialist debt advice is free. Nobody should face a debt problem alone while unwell.
- Housing: if housing is at risk, get advice urgently rather than waiting — early advice usually gives more options.
We cannot promise that any individual will qualify for a particular benefit, adjustment or scheme — that depends on personal circumstances and the decision of the organisation involved.
If concerns are dismissed
Most appointments go well. If they do not, these steps often help:
- Ask the clinician to explain their decision and what would change it.
- Describe the effect on daily life and safety in concrete terms — missed work, not eating, not sleeping, not leaving the house.
- Request another appointment, or an appointment with a different clinician.
- Ask about referral options, or whether self-referral is possible locally.
- Bring written notes, or a supporter or advocate if that is allowed.
- Use the NHS complaints route if the problem is serious or repeated.
- If safety worsens at any point, use the urgent routes at the top of this page rather than waiting for a complaint to be resolved.
Confidentiality and safeguarding
Health professionals normally keep what is discussed private, and they are used to hearing about low mood, self-harm and suicidal thoughts without judgement.
They may, however, need to share relevant information with other professionals if there is a serious risk of harm to the person or to someone else, or if there is a safeguarding concern — for example involving a child or an adult at risk. Nobody can promise complete confidentiality.
In practice this usually means involving people who can help, not removing someone's choices. It is always reasonable to ask at the start: “what would you have to share, and who with?”
After a crisis
Recovering after a crisis takes time and some practical planning:
- arrange follow-up with the GP or mental health team, and keep the appointment
- ask for a medication review if medicines were started or changed
- update the safety plan together with someone trusted
- reduce access to things that could cause harm, such as asking someone to look after medicines or store them elsewhere
- identify the warning signs that came before the crisis
- agree who to contact, and at what point, next time
- arrange practical support — food, bills, childcare, work or study contact
A safety plan is a practical support tool, not a contract or a guarantee. Nobody is failing if they need to use it, or if things become difficult again.
Practical checklist
- Write down the symptoms and how they affect daily life.
- Book a GP appointment, or use an online consultation form.
- Ask for any communication adjustments needed.
- Take a list of all current medicines, including over-the-counter ones.
- Mention any previous episodes of depression and any family history.
- Mention any periods of unusually high energy, irritability or reduced need for sleep.
- Discuss physical symptoms and any long-term health conditions.
- Mention alcohol or drug use honestly.
- Ask what treatment choices are available and what each involves.
- Ask how long treatment may take to help.
- Ask what to do if symptoms get worse before the next appointment.
- Do not stop or change antidepressants suddenly — ask for a planned review.
- Save the urgent-help numbers into your phone.
- Tell one trusted person what is happening.
- Arrange a follow-up appointment before leaving.
- Ask about work, education, money or housing support.
- Create or update a safety plan if that is appropriate.
This checklist is a preparation aid. It is not a diagnostic test and not a suicide-risk score.
Where to find official information
Understanding and treating depression
Getting therapy and NHS services near you
Urgent support
Work and practical support
Related pages on this website
Please speak to a healthcare professional
Sixpence Support UK is an information and signposting service. It cannot diagnose depression, prescribe treatment or provide emergency assistance.
This page provides general information only and is not a substitute for professional medical advice, diagnosis or treatment. Please speak to a GP, pharmacist or another qualified healthcare professional about your own situation, and use the urgent routes above if you are struggling to stay safe.
Reviewed August 2026.
- [1] NHS. Depression in adults — overview · 2026
- [2] NHS. Depression in adults — symptoms · 2026
- [3] NHS. Depression in adults — treatment · 2026
- [4] NICE. Depression in adults: treatment and management (NG222) · 2022, updated
- [5] NICE. Depression in adults — quality standard (QS8) · 2026
- [6] NHS. Antidepressants — overview · 2026
- [7] NHS. NHS Talking Therapies for anxiety and depression (England) · 2026
- [8] NHS. Where to get urgent help for mental health · 2026
- [9] NHS inform (Scotland). Depression · 2026
- [10] NHS 111 Wales. Health advice and services · 2026
- [11] nidirect (Northern Ireland). Mental health services · 2026
- [12] Lifeline (Northern Ireland). Crisis helpline — 0808 808 8000 · 2026
- [13] Samaritans. Contact Samaritans — 116 123 · 2026
- [14] Shout. Text SHOUT to 85258 · 2026
- [15] Childline. Childline — 0800 1111 · 2026
- [16] NHS. Postnatal depression · 2026
- [17] GOV.UK. Access to Work · 2026
- [18] NHS. How to complain to the NHS · 2026
